aesthetic and regenerative treatment

Polynucleotides

THE Stockbridge clinic

Polynucleotides in Edinburgh

Polynucleotides are an advanced aesthetic and regenerative treatment designed to restore skin quality at a cellular level. Using DNA derived polynucleotides, this injectable treatment works by stimulating tissue repair, boosting collagen production and deeply improving skin hydration and elasticity.

Book your consultation today at our aesthetic clinic in Edinburgh to get started with your treatment.
Stockbridge clinic

What is polynucleotide treatment?

£300

Prices starting from

30 mins

Treatment time

1-3 days

Downtime

4 weeks

To show results

6-9 Months

Result duration
Polynucleotide is a revolutionary cosmetic treatment involves the use of polynucleotides (PNs), which are derived from DNA, to rejuvenate and revitalize the skin.

These treatments typically involve injecting polynucleotides into targeted areas to promote tissue repair, stimulate collagen production, and enhance skin hydration and elasticity. The DNA-based compounds in polynucleotides contain growth factors that help regenerate skin cells, improving skin texture, tone, and overall appearance.

This treatment is often used for fine lines, wrinkles, acne scars, and skin aging, offering a non-invasive solution for skin rejuvenation.
THE Stockbridge clinic

How do Polynucleotides Work?

Polynucleotides work by stimulating the skin’s natural regenerative processes at a cellular level. Derived from purified DNA fragments, these biostimulatory compounds act as powerful signalling molecules that encourage skin repair and renewal rather than simply masking signs of ageing.

When injected into the skin, polynucleotides activate fibroblasts, the cells responsible for producing collagen and elastin. This improves skin firmness, elasticity, and structure over time. They also improve hydration by attracting and retaining water within the skin, helping to restore a healthier looking complexion.

Polynucleotides also improve microcirculation and reduce inflammation, supporting tissue healing and strengthening the skin barrier. This makes the treatment particularly effective for delicate or compromised areas, such as under the eyes, where traditional fillers may not be suitable.
The Stockbridge clinic

before and after of polynucleotides

What our patients say about us

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Rod Murray  profile picture
Rod Murray
27 January 2026
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Convenient location, friendly staff, efficient booking and reminders, excellent receptionist in Emma and Karen gives first class treatments.
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Frances
21 January 2026
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Thank you so much to Dr Ben for my recent treatments at the Stockbridge Clinic. As it was my first time having any aesthetic treatments, I was quite nervous, but he was amazing and listened carefully to what I wanted. My results are very natural and I’m so pleased with them. I would highly recommend Dr Ben, especially for anyone considering treatments for the first time!
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George Ashton  profile picture
George Ashton
17 January 2026
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Incredible level of care and attention from Ben and all the professionals at the clinic, taking time to understand the best options for you and delivering a great experience. Would highly recommend
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Debbie Moodie  profile picture
Debbie Moodie
17 January 2026
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I can’t recommend Stockbridge Facial Aesthetic Clinic highly enough. From start to finish, the experience was fantastic. This is a doctor-led clinic, and the team are incredibly professional, knowledgeable, and clearly have a deep understanding of facial aesthetics and injectable treatments. I felt completely confident and at ease in their hands. The clinic itself is relaxed, welcoming, and such a lovely place to visit it genuinely feels calm and reassuring the moment you walk in. Everything is explained thoroughly, and the care and attention to detail really set them apart. I would 100% recommend Stockbridge Facial Aesthetic Clinic to anyone considering aesthetic treatments, and I will definitely be back. A truly great clinic and an all-round excellent experience.
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Jane Taylor  profile picture
Jane Taylor
16 January 2026
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As an older woman with a number of age related skin issues, I was self conscious about my skin and nervous about having treatment. However both Dr.Ben and Karen at the Stockbridge clinic took time to really listen to my concerns and explain what would work best for my skin and my age. I felt really taken care of and the whole experience was so relaxing and pleasant. Highly recommend this clinic.
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Elisa LeNoir
16 January 2026
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My partner and I started seeing Karen for facial laser treatments last year. Along with our skin being fresher and clearer, she has somehow found a way to make me laugh through less-than-enjoyable hair removal treatments! She is so knowledgeable and friendly - Highly recommend Karen and Stockbridge Clinic.
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Izzy Feilding  profile picture
Izzy Feilding
11 January 2026
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I went to The Stockbridge Clinic for a Laser Genesis treatment with Karen and the results have been amazing. The space is beautiful, the team lovely and my skin has never looked better! For skin or aesthetic treatments in Edinburgh I couldn’t recommend The Stockbridge Clinic more.
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Lauren Reid  profile picture
Lauren Reid
10 January 2026
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So glad I found this place. The clinic is clean and staff are very friendly offering great prices. Seeing Karen every month is a breath of fresh air. She really cares for her clients and I trust her in helping me manage my skin. Wouldn’t go anywhere else now I have found her.
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Tara hendry  profile picture
Tara hendry
8 January 2026
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Just got lip filler with Dr Angela and she is a god my lips r amazing… will be back 🤩
Stockbridge clinic

Concerns this will Help

Dark Undereye Circles & Eye Bags

Dark eye bags, also known as dark circles, are caused by a variety of factors, including genetics, aging, and lifestyle habits. Thin skin under the eyes allows blood vessels to show through, leading to a bluish or purplish tint. As we age, skin loses collagen and elasticity, making the blood vessels more prominent. Lack of sleep, stress, and fatigue can worsen the appearance by causing fluid retention and dilated blood vessels.

Dull Skin

Dull skin can be caused by several factors, often linked to a buildup of dead skin cells, poor circulation, or dehydration. As we age, skin cell turnover slows, leading to a lack of radiance. Sun damage can also cause uneven skin tone, making skin appear lackluster.

Lines and Wrinkles

Lines and wrinkles are primarily caused by the natural aging process, as skin loses collagen, elastin, and hyaluronic acid, which are essential for maintaining firmness and elasticity. Sun exposure accelerates this breakdown, leading to photoaging and the development of fine lines, particularly around the eyes and mouth. Repeated facial expressions, such as smiling or frowning, cause dynamic wrinkles that deepen over time. Smoking, poor diet, and dehydration also contribute by reducing skin’s ability to regenerate and maintain moisture.

FAQs

The number of sessions depends on your individual skin concerns and goals. Typically, a course of 3 to 4 sessions spaced 2 to 4 weeks apart is recommended for optimal results. After the initial course, maintenance treatments every 6 to 9 months can help prolong the benefits.

Polynucleotides treatments are generally well tolerated. Most patients experience only mild discomfort during the injection process. Numbing cream can be applied beforehand to make the procedure even more comfortable. Many describe the sensation as a gentle prick rather than sharp pain.

Polynucleotides are not suitable for everyone. The treatment should be avoided by individuals who:

  • Are pregnant or breastfeeding
  • Have active skin infections or inflammation in the treatment area
  • Have a known allergy to any of the ingredients in the product
  • Have certain autoimmune disorders or are on specific medications

A full medical assessment will ensure the treatment is safe for you.

Results from Polynucleotides are gradual and cumulative, improving with each session. Effects typically last 2 to 3 months after a full treatment course, though this can vary depending on skin condition, lifestyle, and age. Regular maintenance sessions can help sustain skin hydration, elasticity, and overall rejuvenation.

No. A frozen appearance is usually caused by excessive dosing or poor placement. At The Stockbridge Clinic, treatments are planned to preserve natural expression while softening overactive muscle movement.

Stockbridge Clinic

Get started with your treatment today

Award-winning & doctor-led aesthetic, regenerative and preventative medicine.
© 2026 The Stockbridge Clinic (Face Clinic Medical Ltd)