Polynucleotides are changing the landscape of regenerative aesthetics. Known by many as the “salmon-sperm facial” or PDRN therapy, these treatments are designed to rejuvenate, hydrate, and repair skin in a way that feels entirely natural. At The Stockbridge Clinic in Edinburgh, patients are embracing this innovative therapy for results that are subtle, sophisticated, and confidence-boosting.
What Are Polynucleotides? Origins & Science Behind the “Salmon-Sperm Facial”
Polynucleotides are fragments of purified DNA, most often derived from salmon. This may sound unusual, yet the science is compelling. Fish DNA is remarkably similar to human DNA, which means the body recognises it, integrates it, and responds with impressive repair mechanisms.
- Originally developed for wound healing
- Safe and biocompatible
- Now widely used in aesthetics for skin rejuvenation
The nickname “salmon-sperm facial” is eye-catching, but it undersells the sophistication of this advanced biostimulatory treatment.
How Do Polynucleotides Work? Skin Repair, Collagen Boosting & Beyond
Inside the skin, polynucleotides act like a biological spark. They signal fibroblasts—the cells responsible for collagen and elastin production, to start working harder. The benefits are threefold:
- Collagen stimulation → firmer, more elastic skin
- Improved hydration → healthier extracellular matrix
- Oxidative stress reduction → protection against premature ageing
The process doesn’t mask ageing. Instead, it restores balance, giving the skin back its ability to renew itself.
Key Benefits of Polynucleotide Treatments
Hydration That Lasts: From Cell Turnover to Glowing Skin
Surface moisturisers fade quickly. Polynucleotides build hydration deep within the skin, leaving a plump, radiant complexion that lasts for months.
Wrinkle & Fine Line Reduction Without the ‘Filled’ Look
Polynucleotides soften lines gradually. Patients notice a refreshed appearance, never artificial, never “overdone.”
Under-Eye Revitalisation: No Puffiness, Just Radiance
The under-eye area is delicate. Polynucleotides improve crepiness, dark circles, and hollows without adding weight or bulk.
Together, these benefits make them a powerful alternative to traditional injectables.
Polynucleotides vs. Traditional Injectables: What Sets Them Apart?
Dermal fillers physically add volume. Anti-wrinkle injections relax muscles. Polynucleotides? They regenerate.
- Natural skin booster, not a volume enhancer
- Improves quality, not just appearance
- Encourages the skin to appear younger, rather than artificially altering it
This makes polynucleotides ideal for those who want long-term rejuvenation that whispers, not shouts.
What to Expect: Treatment Process, Downtime & Frequency
At The Stockbridge Clinic, the process is simple and tailored to your needs.
Needle vs Cannula: Which Delivery Method Works Best?
- Needle: offers pinpoint precision for small areas
- Cannula: covers larger zones with fewer entry points
Recommended Treatment Spacing:
- Initial course: 3 sessions, spaced 3-4 weeks apart
- Maintenance: once every 6-12 months
Downtime & Aftercare:
- Mild swelling or redness for 24-48 hours
- Tiny pin-prick marks that fade quickly
- Return to normal activities almost immediately
A straightforward treatment, yet one that delivers profound change.
Is Polynucleotide Treatment Right for You? Safety, Suitability & Who Should Avoid It
Polynucleotides are suitable for most patients, but there are a few exceptions.
- Not recommended for those with fish allergies
- Safe when delivered by trained medical professionals
- Results are progressive and subtle, building over time
They are especially suited to patients who value natural improvements and gradual rejuvenation over dramatic changes.
Why Choose The Stockbridge Clinic for Polynucleotide Rejuvenation
The Stockbridge Clinic offers more than just a treatment, it offers an experience rooted in expertise and care.
Expert Practitioners Delivering Bespoke Care
Each treatment plan is customised, ensuring precision and safety at every step.
Clinic-Exclusive Techniques & Technology
Access to leading polynucleotide products and innovative methods ensures consistently excellent results.
Client Testimonials: Real Stories, Real Results
Patients describe feeling not only more confident in their skin but also reassured by the clinic’s welcoming, professional environment.
Real-World Results: How Celebrities and Clients Are Loving Polynucleotides
Celebrities have created buzz. Jennifer Aniston. Kim Kardashian. Both reportedly turned to this regenerative treatment.
But it isn’t just for the famous. Everyday men and women are experiencing brighter skin, smoother under-eyes, and renewed confidence. The reason is simple: results look like you, only fresher.
Final Thoughts: A Natural, Regenerative Approach to Youthful Skin
Polynucleotides mark a new era in aesthetics. They don’t freeze or fill. They restore, regenerate, and rejuvenate.
At The Stockbridge Clinic in Edinburgh, patients are guided through this cutting-edge journey with expert care. For those ready to rediscover their skin’s vitality, the first step is simple:
Book a consultation today and experience the future of skin rejuvenation.
FAQs
1. How long do results last?
Most patients enjoy results for 6-12 months. Maintenance keeps skin refreshed.
2. Can polynucleotides be combined with other treatments?
Yes. They pair perfectly with microneedling, laser therapy, and skin boosters.
3. Are they safe?
Yes. When carried out by a trained practitioner, they are considered very safe with minimal downtime.
4. Who shouldn’t have them?
Those with fish allergies or certain medical conditions may not be suitable. A consultation will confirm.
5. When will I notice improvements?
Subtle changes appear within weeks. Full results emerge gradually as collagen and hydration increase.